BDBM65039 BDBM256703::US10053456, 85::US10414761, Example 85::US10968213, Example 85::US9487511, 116::US9718814, 85::US9920047, 85

SMILES Cc1nnc(NC(=O)c2cc(cs2)[C@H]2C[C@@H]2NC2CCC2)s1

InChI Key InChIKey=ALKUEFQXLXYBPP-NEPJUHHUSA-N

Data  33 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 65039   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM65039(BDBM256703 | US10053456, 85 | US10414761, Example ...)
Affinity DataIC50:  810nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM65039(BDBM256703 | US10053456, 85 | US10414761, Example ...)
Affinity DataIC50:  810nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM65039(BDBM256703 | US10053456, 85 | US10414761, Example ...)
Affinity DataIC50:  810nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM65039(BDBM256703 | US10053456, 85 | US10414761, Example ...)
Affinity DataIC50:  810nMAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM65039(BDBM256703 | US10053456, 85 | US10414761, Example ...)
Affinity DataIC50:  810nMAssay Description:LSD1: A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM65039(BDBM256703 | US10053456, 85 | US10414761, Example ...)
Affinity DataIC50:  810nMAssay Description:LSD1: A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and...More data for this Ligand-Target Pair
In DepthDetails US Patent